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8.2.2 Triptan-overuse headache


Headache occurring on 15 or more days/month in a patient with a pre-existing primary headache and developing as a consequence of regular use of one or more triptans on 10 or more days/month for more than 3 months. It usually, but not invariably, resolves after the overuse is stopped.

Diagnostic criteria:
  1. Headache fulfilling criteria for 8.2 Medication-overuse headache
  2. Regular intake of one or more triptans1, in any formulation, on ≥10 days/month for >3 months.

The triptan(s) will usually be specified in parenthesis.


Triptan overuse by people with 1.1 Migraine without aura or 1.2 Migraine with aura may increase attack frequency to that of 1.3 Chronic migraine. Evidence suggests that this occurs sooner with triptan overuse than with ergotamine overuse.