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8.2.4 Opioid-overuse headache

Diagnostic criteria:
  1. Headache fulfilling criteria for 8.2 Medication-overuse headache
  2. Regular intake of one or more opioids1 on ≥10 days/month for >3 months.

The opioid(s) should be specified in parenthesis.


Prospective studies indicate that patients overusing opioids have the highest relapse rate after withdrawal treatment.