Immediate histamine-induced headache

Diagnostic criteria:
  1. Any headache fulfilling criterion C
  2. Histamine has been administered
  3. Evidence of causation demonstrated by all of the following:
    1. headache has developed within 1 hour of histamine absorption
    2. headache has resolved within 1 hour after absorption of histamine has ceased
    3. headache has at least one of the following four characteristics:
      • a) bilateral
      • b) mild to moderate intensity
      • c) pulsating quality
      • d) aggravated by physical activity
  4. Not better accounted for by another ICHD-3 diagnosis.