Description:

Headache caused by a pituitary adenoma and hypothamic or pituitary hyper- or hyposecretion, usually accompanied by disorder of temperature regulation, abnormal emotional state and/or altered thirst or appetite. It remits after successful treatment of the underlying disorder.

Diagnostic criteria:
  1. Any headache fulfilling criterion C
  2. Hypothalamic or pituitary hyper- or hyposecretion associated with pituitary adenoma has been demonstrated1
  3. Evidence of causation demonstrated by at least two of the following:
    1. headache has developed in temporal relation to onset of hypothalamic or pituitary hyper- or hyposecretion
    2. either or both of the following:
      • a) headache has significantly worsened in parallel with worsening of the hypothalamic or pituitary hyper- or hyposecretion
      • b) headache has significantly improved in parallel with improvement in the hypothalamic or pituitary hyper- or hyposecretion
    3. headache is associated with at least one of the following:
      • a) disorder of temperature regulation
      • b) abnormal emotional state
      • c) altered thirst and/or appetite
  4. Not better accounted for by another ICHD-3 diagnosis.
Note:

1. Including prolactin, growth hormone (GH) and/or adrenocorticotropic hormone (ACTH) hypersecretion.