7.3.1 Headache attributed to neurosarcoidosis


Headache caused by and associated with other symptoms and signs of neurosarcoidosis.

Diagnostic criteria:
  1. Any headache fulfilling criterion C
  2. Neurosarcoidosis has been diagnosed
  3. Evidence of causation demonstrated by at least two of the following:
    1. headache has developed in temporal relation to the onset of the neurosarcoidosis
    2. either or both of the following:
      • a) headache has significantly worsened in parallel with worsening of the neurosarcoidosis
      • b) headache has significantly improved in parallel with improvement in the neurosarcoidosis
    3. headache is accompanied by one or more cranial nerve palsies
  4. Not better accounted for by another ICHD-3 diagnosis.

Other manifestations of neurosarcoidosis include aseptic meningitis, cranial nerve lesions, intracranial space-occupying lesion(s) on brain MRI, periventricular inflammatory focal lesions and/or homogeneously enhancing mass lesions on brain or spinal MRI that are confirmed on biopsy as non-caseating granulomas.